Cholinesterase, Butyryl Product Information

Source: Horse Serum

I.U.B.: 3.1.1.8

Butyrl Cholinesterase catalyzes the hydrolysis of a number of choline esters according to the following reaction:

Acylcholine + H₂O → choline + acid

It is a tetrameric glycoprotein with four subunits of equal size, each having a molecular weight of 110 kDa. Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine. Unlike acetyl cholinesterase, it does not hydrolyze D-≥-methyl acetylcholine. It is inhibited by 10^-5 M physostigmine, numerous organophosphate esters, the carbamate derivates and quaternary ammonium salts.

Stability/Storage: Stable for 2 years at 2-8°C. Store at 2-8°C.

Unit Definition: 1 unit hydrolyzes 1≥mole of acetylchoine per minute at 25°C, pH 7.4.