Lactate Dehydrogenase Product Information

Source: Recombinant, rabbit muscle produced in E. coli

I.U.B.: 1.1.1.27

Mammalian lactate dehydrogenases (LDH) exist as five tetrameric isozymes composed of combinations of two different subunits. The H subunit predominates in heart muscle, which is geared for aerobic oxidation of pyruvate. The M subunit predominates in skeletal muscle and is concerned more with anaerobic metabolism and pyruvate reduction.

Unit Definition: One Unit oxidizes one micromole of NADH per minute at 25°C, pH 7.3

Please note that the source of this product has changed from native rabbit muscle form to a recombinant for expressed in E. coli.  The recombinant enzyme meets or exceeds the specifications of the native enzyme previously supplied.