Trypsinogen References

• Abita, J., and Lazdunski, M.: On the Structural and Functional Role of Carboxylates in Chymotrypsinogen A: A Comparison with Chymotrypsin, Trypsinogen and Trypsin , Biochem Biophys Res Commun 35, 707, 1969
• Abuchowski, A., and Davis, F.: Preparation and Properties of Polyethylene Glycol-Trypsin Adducts , Biochim Biophys Acta 578, 41, 1979
• Alagiri, S., and Singh, T.: Stability and Kinetics of a Bifunctional Amylase/ Trypsin Inhibitor , Biochim Biophys Acta 1203, 77, 1993
• Anson, M.: The Estimation of Pepsin, Trypsin, Papain and Cathepsin with Hemoglobin, J Gen Physiol 22, 79, 1938
• Antonini, E., and Ascenzi, P.: The Mechanism of Trypsin Catalysis at Low pH. Proposal for a Structural Model , J Biol Chem 256, 12449, 1981
• Arakawa, T., Hung, L., McGinley, M., Rohde, M., and Narhi, L.: Induced Resistance of Trypsin to Sodium Dodecylsulfate upon Complex Formation with Trypsin Inhibitor , J Protein Chem 11, 171, 1992
• Arentoft, A., Frokiaer, H., Michaelsen, S., Sorensen, H., and Sorensen, S.: High-performance Capillary Electrophoresis for the Determination of Trypsin and Chymotrypsin Inhibitors and Their Association with Trypsin, Chymotrypsin and Monoclonal Antibodies , J Chromatogr A 652, 189, 1993
• Arnon, R., and Neurath, H.: An Immunological Approach to the Study of Evolution of Trypsins , Proc Natl Acad Sci U S A 64, 1323, 1969
• Ascenzi, P., Amiconi, G., Bolognesi, M., Menegatti, E., and Guarneri, M.: Trypsin Activation. Effect of the Ile-Val Dipeptide Concentration on Kazal Inhibitor Binding to Bovine Trypsinogen , Biochim Biophys Acta 832, 378, 1985
• Ascenzi, P., Bolognesi, M., Guarneri, M., Menegatti, E., and Amiconi, G.: Benzamidine as a Spectroscopic Probe for the Primary Specificity Subsite of Trypsin-like Proteinases , Mol Cell Biochem 64, 139, 1984
• Ascenzi, P., Menegatti, E., Bortolotti, F., Guarneri, M., and Antonini, E.: Steady-state and Pre-steady-state Kinetics of the Trypsin-catalyzed Hydrolysis of a-CBZ-L-Lysine-p-nitrophenyl Ester , Biochim Biophys Acta 658, 158, 1981
• Asgeirsson, B., Fox, J., and Bjarnason, J.: Purification and Characterization of Trypsin from the Poikilotherm Gladus morhua , Eur J Biochem 180, 85, 1989
• Ashton, D., Ashcroft, A., Beddell, C., Green, B., and Oliver, R.: On the Analysis of Bovine Trypsin by Electrospray-Mass Spectrometry , Biochem Biophys Res Commun 199, 694, 1994
• Atassi, P.: Surface-simulation Synthesis of the Substrate-binding Site of an Enzyme. Demonstration with Trypsin , Biochem J 226, 477, 1985
• Baines, N., Baird, J., and Elmore, D.: The Kinetics of Hydrolysis of Derivatives of Arginine, Homoarginine and Ornithine by Trypsin , Biochem J 90, 470, 1964
• Balls, A.: Concerning Trypsinogen , Proc Natl Acad Sci U S A 53, 392, 1965
• Bar-Eli, A., and Katchalski, E.: A Water-Insoluble Trypsin Derivative and its Use as a Trypsin Column , Nature 188, 856, 1960
• Bartholomew, J., Handley, C., and Lowther, D.: The Effects of Trypsin Treatment on Proteoglycan Biosynthesis of Bovine Articular Cartilage , Biochem J 227, 429, 1985
• Beardslee, R., and Zahnley, J.: A Simple Preparation of beta-Trypsin Based on a Colorimetric Study of the Thermal Stabilities of alpha and beta Trypsin , Arch Biochem Biophys 158, 806, 1973
• Berezin, I., Kazanskaya, N., Klyosov, A., and Svedas, V.: The Mechanism of the alpha-Chymotrypsin and Trypsin-Catalyzed Hydrolysis of Amides. Evidence for the Participation of the Active Serine in the Amidase Activity of Trypsin , Eur J Biochem 38, 529, 1973
• Bergmann, M., and Fruton, J.: Advances in Enzymology Vol. 63,, , , 1941
• Berlin, I., and Neujahr, H.: Studies of Controlled Lysis of Washed Cell Suspensions of Lactobacillus fermenti and Preparation of Membrane-like Fragments by a Combined Trypsin-Lysozyme Treatment , Acta Chem Scand 22, 2972, 1968
• Berliner, L., and Wong, S.: Evidence Against Two "pH-locked" Conformations of Phosphorylated Trypsin , J Biol Chem 248, 1118, 1973
• Berliner, L., and Wong, S.: Spin-labeled Sulfonyl Fluorides as Active Site Probes of Protease Structure. I. Comparison of the Active Site Environments in alpha-Chymotrypsin and Trypsin , J Biol Chem 249, 1668, 1974
• Bier, M., and Nord, F.: On the Mechanism of Enzyme Action. 46. The Effect of Certain Ions on Crystalline Trypsin and Reinvestigation of its Isoelectric Point , Arch Biochem Biophys 33, 320, 1951
• Borovsky, D., Schlein, Y.: Quantitative Determination of Trypsinlike and Chymotrypsinlike Enzymes in Insects, Arch Insect Biochem Physiol 8, 249, 1988
• Bricteux-Gregoire, S., Schyns, R., and Florkin, M.: N-Terminal Amino Acid Sequence of Trypsinogen from the Elephant Seal Mirounga leonine L. (Carnivora) , Biochim Biophys Acta 351, 87, 1974
• Bricteux-Gregoire,S., Schyns, R., Florkin, M., Emmens, R. Welling, G., and Beintema, J.: N-Terminal Amino Acid Sequence of Trypsinogen from the Lesser Rorqual Balaenoptera acutorostrata (Cetacea) , Biochim Biophys Acta 386, 244, 1975
• Brines, R., and Brock, J.: The Effect of Trypsin and Chymotrypsin on the in Vitro Antimicrobial and Iron-Binding Properties of Lactoferrin in Human Milk and Bovine Colostrum , Biochim Biophys Acta 759, 229, 1983
• Brown, W., and Wold, F.: Alkyl Isocyanates as Active-Site-Specific Reagents for Serine Proteases. Identification of the Active-Site Serine as the Site of Reaction , Biochemistry 12, 835, 1973
• Brown, W., and Wold, F.: Alkyl Isocyanates as Active-Site-Specific Reagents for Serine Proteases. Reaction Properties , Biochemistry 12, 828, 1973
• Brunger, A., Huber, R., and Karplus, M.: Trypsinogen-Trypsin Transition: A Molecular Dynamics Study of Induced Conformational Change in the Activation Domain , Biochemistry 26, 5153, 1987
• Byrne, R., and Scanu, A.: Soluble and Immobilized Trypsins as Structural Probes of Human Plasma High-Density Lipoproteins: Enzyme Properties and Kinetics of Proteolysis , Biochemistry 22, 2894, 1983
• Caldwell, R.: Effect of Calcium and Phytic Acid on the Activation of Trypsinogen and the Stability of Trypsin, J Agric Food Chem 40, 43, 1992
• Castaneda-Agullo, M., and Del Castillo, L.: The Influence of the Medium Dielectric Strength upon Trypsin Kinetics , J Gen Physiol 42, 617, 1959
• Chambers, J., Christoph, G., Krieger, M., Kay, L., and Stroud, R.: Silver Ion Inhibition of Serine Proteases. Crystallographic Study of Silver-Trypsin , Biochem Biophys Res Commun 59, 70, 1974
• Chang, A., and Slayman, C.: A Structural Change in the Neurospora Plasma Membrane [H⁺] ATPase Induced by N-Ethylmaleimide , J Biol Chem 265, 15531, 1990
• Chen, T., and Reisler, E.: Tryptic Digestion of Rabbit Skeletal Myofibrils: An Enzymatic Probe of Myosin Cross-Bridges , Biochemistry 23, 2400, 1984
• Christensen, U., and Sottrup-Jensen, L.: Mechanism of alpha-2-Macroglobulin - Proteinase Interaction. Studies with Trypsin and Plasmin , Biochemistry 23, 6619, 1984
• Coats, E.: Comparative Inhibition of Thrombin, Plasmin, Trypsin, and Complement by Benzamidines Using Substituent Constants and Regression Analysis , J Med Chem 16, 1102, 1973
• Cohen, W., Lache, M., and Erlanger, B.: The Reactivation of Diethylphosphoryltrypsin , Biochemistry 1, 686, 1962
• Coletta, M., Ascenzi, P., Amiconi, G., Bolognesi, M., Guarneri, M., and Menegatti, E.: Bovine Trypsinogen Activation. A Thermodynamic Study , Biophys Chem 37, 355, 1990
• Compton, P., and Fink, A.: Low-Temperature Reaction of Trypsin with p-Nitroanilide Substrates. Tetrahedral Intermediate Formation on Enzyme Isomerization , Biochemistry 23, 2989, 1984
• Craik, C., Roczniak, S., Largman, C., and Rutter, W.: The Catalytic Role of the Active Site Aspartic Acid in Serine Proteases , Science 237, 909, 1987
• Cunningham, L.: Molecular-Kinetic Properties of Crystalline Diisopropyl Phosphoryl Trypsin , J Biol Chem 211, 13, 1954
• Delaage, M., and Lazdunski, M.: Different Molecular Species of Bovine Trypsinogen and Trypsin (French) , Biochim Biophys Acta 105, 608, 1965
• DeLarco, J., and Liener, I.: The Involvement of an Arginine Residue of Trypsin in Its Interaction with the Kunitz Soybean Trypsin Inhibitor , Biochim Biophys Acta 303, 274, 1973
• DelCastillo, L., Davila, G., Dorantes, L., Oliver, C., Ibarra, R., and Castaneda-Agullo, M.: The Influence of a Free alpha-Ammonium Group in the Substrate Upon Trypsin-catalyzed Transesterification , Biochim Biophys Acta 191, 354, 1969
• Delvaux, A., Vanderelst, L., and Octave, J.: Inhibition of Trypsin by the beta-Amyloid Protein Precursor - A Comparative Study Between Transfected Cells, Human Brain and Cerbrospinal Fluid , F.E.B.S. Lett. 297, 124, 1992
• Desnuelle, P.: Trypsin, The Enzymes Vol. 4,P. Boyer, H. Lardy, and K. Myrback, Academic Press, NY, 119, 1960
• Erlanager, B., Kokowsky, N., and Cohen, W.: The Preparation and Properties of Two New Chromogenic Substrates of Trypsin , Arch Biochem Biophys 95, 271, 1961
• Feinstein, G.: Purification of Trypsin by Affinity Chromatography on Ovomucoid-sepharose Resin , F.E.B.S. Lett. 7, 353, 1970
• Figarella, C., Negri, G., and Guy, O.: The Two Human Trypsinogens. Inhibition Spectra of the Two Human Trypsins Derived from Their Purified Zymogens , Eur J Biochem 53, 457, 1975
• Finer-Moore, J., Kossiakoff, A., Hurley, J., Earnest, T., and Stroud, R.: Solvent Structure in Crystals of Trypsin Determined by X-Ray and Neutron Diffraction , Proteins, Structure Function & Genetics 12, 203, 1992
• Finotti, P.: Separation by Heparin-affinity Chromatography of Catalytically Active and Inactive Forms of Trypsin which Retain the (Na-K)ATPase Stimulating Property , Clin Chim Acta 256, 37, 1996
• Ford, J., Chambers, R., and Cohen, W.: An Active-site Titration Method for Immobilized Trypsin , Biochim Biophys Acta 309, 175, 1973
• Fraenkel-Conrat, H., Bean, R., and Lineweaver, H.: Essential Groups for the Interaction of Ovomucoid (Egg White Trypsin Inhibitor) and Trypsin, and for Tryptic Activity, J Biol Chem 177, 385, 1949
• Fraenkel-Conrat, H., Bean, R., Ducay, E., and Olcott, H.: Isolation and Characterization of Trypsin Inhibitor from Lima Beans , Arch Biochem Biophys 37, 393, 1952
• Fromherz, P., and Marcheva, D.: Enzyme Kinetics at a Lipid Protein Monolayer. Induced Substrate Inhibition of Trypsin , F.E.B.S. Lett. 49, 329, 1975
• Fujioka,T., Tanizawa, K., and Kanaoka, Y.: Specific Spin-Labelling at Trypsin Active Site. Application of "Inverse Substrate" to the Structural Analysis of the Active Site , Biochim Biophys Acta 612, 205, 1980
• Gabel, D., Vretblad, P., Axen, R., and Porath, J.: Insolubilized Trypsin with Activity in 8 M Urea , Biochim Biophys Acta 214, 561, 1970
• Gaudin, J., and Stevens, F.: The Trypsin and Chymotrypsin Inhibitory Capacity of Human and Bovine alpha-Crystallin , F.E.B.S. Lett. 48, 72, 1974
• Gavilanes-Ruiz, M., Tommasino, M., and Capaldi, R.: Structure-Function Relationships of the Escherichia coli ATP Synthase Probed by Trypsin Digestion , Biochemistry 27, 603, 1988
• Gendry, P., and Launay, J.: Pancreatic Anionic Trypsin - Evidence for the Existence of a 30-kDa Form , Comp Biochem Physiol B 102, 37, 1992
• Geratz, J., Cheng, M., and Tidwell, R.: New Aromatic Diamidines with Central alpha-oxyalkane or alpha-W-Dioxyalkane Chains. Structure-Activity Relationships for the Inhibition of Trypsin, Pancreatic Kallikrein, and Thrombin and for the Inhibition of the Overall Coagulation Process , J Med Chem 18, 477, 1975
• Ghiron, C., Longworth, J., and Ramachandran, J.: Triplet-Triplet Energy Transfer in alpha-Trypsin , Proc Natl Acad Sci U S A 70, 3703, 1973
• Glenner, G., Hopsu, V., and Cohen, L.: New Substrates of Trypsin and Some Trypsin-like Enzymes , J Histochem Cytochem 12, 545, 1964
• Gomez, J., Birnbaum, E., and Darnall, D.: The Metal Ion Acceleration of the Conversion of Trypsinogen to Trypsin. Lanthanide Ions as Calcium Ion Substitutes , Biochemistry 13, 3745, 1974
• Graf, L., Craik, C., Patthy, A., Roczniak, S., Fletterick, R., and Rutter, W.: Selective Alteration of Substrate Specificity by Replacement of Aspartic Acid-189 with Lysine in the Binding Pocket of Trypsin , Biochemistry 26, 2616, 1987
• Graf, L., Hegyi, G., Liko, I., Hep, J., Medzihradszky, K., Craik, C., and Rutter, W.: Structural and Functional Integrity of Specificity and Catalytic Sites of Trypsin , Int J Pept Protein Res 32, 512, 1988
• Green, M., Gladner, J., Cunningham, L., and Neurath, H.: The Effects of Divalent Cations on the Enzymatic Activities of Trypsin and alpha-Chymotrypsin, J Am Chem Soc 74, 2122, 1952
• Green, S., and Neurath, H.: Proteolytic Enzymes, The Proteins Vol. II,H. Neurath, Academic Press, NY, 1057, 1954
• Greenbaum, L., Hirshkowitz, A., and Schoichet, I.: The Activation of Trypsinogen by Cathepsin B , J Biol Chem 234, 2885, 1959
• Griffiths, A., and Brechner, A.: Protection Afforded to Trypsin and Trypsinogen by Calcium Ion from Inactivation by Chlorambucil , Proc Soc Exp Biol Med 142, 1045, 1973
• Hedstrom, L., Szilagyi, L., and Rutter, W.: Converting Trypsin to Chymotrypsin - the Role of Surface Loops , Science 255, 1249, 1992
• Helmqvist, B., Borgstrsm, A., and Ohlsson, K.: Interactions in Vitro and in vivo Between Anionic and Cationic Porcine Trypsin and Porcine Plasma Proteinase Inhibitors , Biol Chem Hoppe Seyler 369, 1331, 1988
• Hermodson, M., Ericsson, L., Neurath, H., and Walsh, K.: Determination of the Amino Acid Sequence of Porcine Trypsin by Sequenator Analysis , Biochemistry 12, 3146, 1973
• Hess, G., and Wainfan, E.: Enzymatically Active Components in Trypsin Autolysates, J Am Chem Soc 80, 501, 1958
• Higaki, J., and Light, A.: Independent Refolding of Domains in the Pancreatic Serine Proteinases , J Biol Chem 261, 10606, 1986
• Hixson, H., and Nishikawa, A.: Affinity Chromatography: Purification of Bovine Trypsin and Thrombin , Arch Biochem Biophys 154, 501, 1973
• Hofmann, T.: The Purification and Properties of Fragments of Trypsinogen Obtained by Cyanogen Bromide Cleavage , Biochemistry 3, 356, 1964
• Hofstee, B.: Fatty Acid Esters as Substrates for Trypsin and Chymotrypsin , Biochim Biophys Acta 24, 211, 1957
• Holeysovsky, V., Keil, B., and Sorm, F.: Location of Reactive Tyrosine Residues in Trypsin , F.E.B.S. Lett. 3, 107, 1969
• Houston, L., and Walsh, K.: The Transient Inactivation of Trypsin by Mild Acetylation with N-Acetylimidazole , Biochemistry 9, 156, 1970
• Hummel, B.: A Modified Spectrophotometric Determination of Chymotrypsin, Trypsin and Thrombin , Can J Biochem Physiol 37, 1393, 1959
• Ikeno, K., Ikeno, T., Kazuya, H., and Ishiguro, I.: Purification and Characterization of a Trypsin-like Protease in the Submandibular Gland of Rats , J. Biochem. 99, 1219, 1986
• Inagami, T., and Sturtevant, J.: Nonspecific Catalyses by alpha-Chymotrypsin and Trypsin , J Biol Chem 235, 1019, 1960
• Isackson, P., Beaudoin, J., Hermodson, M., and Reeck, G.: Production of HMG-3 by Limited Trypsin Digestion of Purified High-Mobility-Group Nonhistone Chromatin Proteins , Biochim Biophys Acta 748, 436, 1983
• Iwaki, K., Ogawa, M., Kitahara, T., Tanaka, S., and Kosaki, G.: Influence of Inactivation of Trypsin on Immunoreactivity and Serum Immunoreactive Trypsin Concentration Measured by Radioimmunoassay , Enzyme 29, 153, 1983
• Jameson, G., and Elmore, D.: Affinity Chromatography of Bovine Trypsin. A Rapid Separation of Bovine alpha and beta Trypsin , Biochem J 141, 555, 1974
• Jeno, P., Green, J., and Lentze, M.: Specificity Studies on Enteropeptidase Substrates Related to the N-Terminus of Trypsinogen , Biochem J 241, 721, 1987
• Jones, R.: Unusual Fucoidin-Binding Properties of Chymotrypsinogen and Trypsinogen , Biochim Biophys Acta 1037, 227, 1990
• Jurasek, L., and Smillie, L.: The Amino Acid Sequence of Streptomyces griseus Trypsin II. The Tryptic Peptides , Can J Biochem 52, 382, 1974
• Kasai, K., and Ishii, S.: Unimportance of Histidine and Serine Residues of Trypsin in the Substrate Binding Function Proved by Affinity Chromatography , J. Biochem. 74, 631, 1973
• Kawasaki, H., Kurosu, Y., Kasai, H., Isobe, T., and Okuyama, T.: Limited Digestion of Calmodulin with Trypsin in the Presence or Absence of Various Metal Ions , J. Biochem. 99, 1409, 1986
• Kay, C., Smillie, L., and Hilderman, F.: The Molecular Weight of Trypsinogen , J Biol Chem 236, 118, 1961
• Keil -Dlouha, V., and Keil, B.: A Tryptophan Residue in Bovine Trypsinogen Essential for its Potential Enzymic Activity and for its Interaction with Basic Pancreatic Trypsin Inhibitor , J Mol Biol 67, 495, 1972
• Keil-Dlouha, V., Zylber, N., Imhoff, J., Tong, N., and Keil, B.: Proteolytic Activity of Pseudotrypsin , F.E.B.S. Lett. 16, 291, 1971
• Keil-Dlouha, V., Zylber, N., Tong, N., and Keil, B.: Cleavage of Glucagon by alpha- and beta-Trypsin , F.E.B.S. Lett. 16, 287, 1971
• Keller, P., Cohen, E., and Neurath, H.: The Proteins of Bovine Pancreatic Juice , J Biol Chem 233, 344, 1958
• Knights, R., and Light, A.: Enhanced Reactivity of Disulfide-Modified Trypsinogen Toward an Active-Site Directed Reagent , Biochem Biophys Res Commun 61, 1161, 1974
• Knights, R., and Light, A.: Sepharose-Bound Trypsin and Activated Sepharose-Bound Trypsinogen. Studies with Small and Large Substrates , Arch Biochem Biophys 160, 377, 1974
• Kobayashi, R., and Ishii, S.: The Trypsin-catalyzed Hydrolysis of Some L-alpha-amino-lacking Substrates , J. Biochem. 75, 825, 1974
• Konishi, K., and Takagi, T.: Activation of the Fibrin Stabilizing Factor by Trypsin and Some of Its Properties After Activation , J. Biochem. 65, 281, 1969
• Kossiakoff, A.: Protein Dynamics Investigated by the Neutron Diffraction-Hydrogen Exchange Technique , Nature 296, 713, 1982
• Kossiakoff, A.: Tertiary Structure Is a Principal Determinant to Protein Deamidation , Science 240, 191, 1988
• Kossiakoff, A., Chambers, J., Kay, L., and Stroud, R.: Structure of Bovine Trypsinogen at 1.9 Å Resolution , Biochemistry 16, 654, 1977
• Kostka, V., and Carpenter, F.: Inhibition of Chymotrypsin Activity in Crystalline Trypsin Preparations , J Biol Chem 239, 1799, 1964
• Krebs, G., and Jacquot-Armond, Y.: Interactions between Trypsin, alpha-2 Macroglobulin and Soybean Trypsin Inhibitor , Biochem Biophys Res Commun 55, 929, 1973
• Kubiak, T., and Cowburn, D.: Trypsin-Catalyzed Formation of Pig Des-(23-63)-Proinsulin from Desoctapeptide-(B23-30)-insulin , Biochem J 234, 665, 1986
• Kunitz, M.: Isolation of a Crystalline Protein Compound of Trypsin and of Soybean Trypsin Inhibitor, J Gen Physiol 30, 311, 1947
• Kunitz, M., and Northrop, J.: Isolation from Beef Pancreas of Crystalline Trypsinogen, Trypsin, a Trypsin Inhibitor and an Inhibitor-Trypsin Compound, J Gen Physiol 19, 991, 1936
• Kunugi, S., Fukuda, M., and Ise, N.: Pressure Dependence of Trypsin-Catalyzed Hydrolyses of Specific Substrates , Biochim Biophys Acta 704, 107, 1982
• Leef, J., and Larner, J.: Insulin-mimetic Effect of Trypsin on the Insulin Receptor Tyrosine Kinase in Intact Adipocytes , J Biol Chem 262, 14837, 1987
• Liem, R., and Scheraga, H.: Mechanism of Action of Thrombin or Fibrinogen. IV. Further Mapping on the Active Sites of Thrombin and Trypsin , Arch Biochem Biophys 160, 333, 1974
• Liener, I.: Chromatographic Studies on Trypsin, Trypsinogen and the Activation Process , Arch Biochem Biophys 88, 216, 1960
• Liepinsh, E., and Otting, G.: Specificity of Urea Binding to Proteins, J Am Chem Soc 116, 9670, 1994
• Light, A., and Fonseca, P.: The Preparation and Properties of the Catalytic Subunit of Bovine Enterokinase , J Biol Chem 259, 13195, 1984
• Light, A., and Odorzynski, T.: Refolding of Bovine Trypsinogen with One and Two Disulfide Bonds Reduced and Carboxymethylated , J Biol Chem 254, 9162, 1979
• Lindley, H.: A New Synthetic Substrate for Trypsin and Its Application to the Determination of the Amino-acid Sequence of Proteins , Nature 178, 647, 1956
• Liu, K., Markakis, P., and Smith, D: Trypsin Inhibition by Free Fatty Acids and Stearoyl-CoA, J Agric Food Chem 38, 1475, 1990
• Luong, J., Male, K., and Nguyen, A.: A Continuous Affinity Ultrafiltration Process for Trypsin Purification , Biotechnol Bioeng 31, 516, 1988
• Luong, J., Male, K., and Nguyen, A.: Synthesis and Characterization of a Water-Soluble Affinity Polymer for Trypsin Purification , Biotechnol Bioeng 31, 439, 1988
• MacKenzie, N., Malthouse, J., and Scott, A.: Cryoenzymology of Trypsin. ¹³C-NMR Detection of an Acyl-trypsin Intermediate in the Trypsin-Catalyzed Hydrolysis of a Highly Specific Substrate at Subzero Temperature , Biochem J 219, 437, 1984
• Mallory, P., and Travis, J.: Human Pancreatic Enzymes. Characterization of Anionic Human Trypsin , Biochemistry 12, 2847, 1973
• Mannhalter, C., Schiffman, S., and Jacobs, A.: Trypsin Activation of Human Factor XI , J Biol Chem 255, 2667, 1980
• Mares-Guia, M., and Figueiredo, A.: Thermodynamics of the Hydrophobic Interaction in the Active Center of Trypsin. Investigation with Amidines and Guanidines , Biochemistry 9, 3223, 1970
• Mares-Guia, M., and Shaw, E.: Studies on the Active Center of Trypsin. The Binding of Amidines and Guanidines as Models of the Substrate Side Chain , J Biol Chem 240, 1579, 1965
• Mares-Guia, M., Silva, E., and Tunes, H.: Competitive Inhibition of the D-Isomer in Racemic Mixtures Used as Substrate in Kinetic Studies: A Simple Method for Data Treatment , Arch Biochem Biophys 228, 278, 1984
• Markwardt, F., Richter, M., Walsmann, P., and Landmann, H.: The Inhibition of Trypsin, Plasmin, and Thrombin by Benzyl - 4 - Guanidinobenzoate and 4' - Nitrobenzyl 4 - Guanidinobenzoate , F.E.B.S. Lett. 8, 170, 1970
• Maroux, S., Rovery, M., and Desnuelle, P.: Hydrolysis by Bovine Trypsin of Some Aromatic Bonds in High Molecular Weight Peptides , Biochim Biophys Acta 122, 147, 1966
• Martin, B., Feinman, R., and Detwiler, T.: Platelet Stimulation by Thrombin and Other Proteases , Biochemistry 14, 1308, 1975
• Martin, C., Golubow, J., and Axelrod, A.: The Hydrolysis of Carbobenzoxy-L-tyrosine p-Nitrophenyl Ester by Various Enzymes , J Biol Chem 234, 1718, 1959
• Martinek, K., Goldmacher, V., Klibanov, A., and Berezin, I.: Denaturing Agents (Urea and Acrylamide) Protect Enzymes Against Irreversible Thermoinactivators: A Study with Native and Immobilized alpha-Chymotrypsin and Trypsin , F.E.B.S. Lett. 51, 152, 1975
• Matsushima, A.: States of Amino Acid Residues in Proteins. XVII. Tyrosine, Histidine and Tryptophan Residues in Bovine Trypsin in the Presence and Absence of Benzamidine , J. Biochem. 65, 961, 1969
• Maurel, P., Hoa, G., and Douzon, P.: The pH Dependence of the Tryptic Hydrolysis of Benzoyl-L-arginine Ethyl Ester in Cooled Mixed Solvents , J Biol Chem 250, 1376, 1975
• Mayer, M., Khassis, S., and Shafrir, E.: Determination of Trypsin by Its Accelerating Effect on the Onset of Trypsinogen Activation , Anal Biochem 58, 25, 1974
• McMurray, J., and Dyckes, D.: Evidence for Hemiketals as Intermediates in the Inactivation of Serine Proteinases with Halomethyl Ketones , Biochemistry 25, 2298, 1986
• Menegatti, E., Guarneri, M., Bolognesi, M., Ascenzi, P., and Amiconi, G.: Activating Effect of the Ile-Val Dipeptide on the Catalytic Properties of Bovine Trypsinogen , Biochim Biophys Acta 832, 1, 1985
• Mitin, Y., Zapevalova, N., and Gorbunova, E.: New Approaches to Peptide Synthesis with the Help of Trypsin , Biomed Biochim Acta 50, S74, 1991
• Mohan, S., Jennings, J., Linkhart, T., and Baylink, D.: Primary Structure of Human Skeletal Growth Factor: Homology with Human Insulin-like Growth Factor-II , Biochim Biophys Acta 966, 44, 1988
• Morgan, P., Walsh, A., and Neurath, H.: Inactivation of Trypsinogen by Methane Sulfonyl Fluoride , F.E.B.S. Lett. 41, 108, 1974
• Moroi, M., and Yamasaki, M.: Mechanism of Interaction of Bovine Trypsin with Human alpha-1-Antitrypsin , Biochim Biophys Acta 359, 130, 1974
• Muller, O., and Yamanouchi, I.: Stable Solutions of Trypsin , Arch Biochem Biophys 76, 328, 1958
• Muramatu, M., and Fujii, S.: Inhibitory Effects of omega-Amino Acid Esters on the Activities of Trypsin, Plasmin, and Thrombin , J. Biochem. 65, 17, 1969
• Murray, P., Silberstein, S., Cantore, M., and Passeron, S.: A Radioactive Method for the Measurement of Trypsin and Trypsin-like Activities , Anal Biochem 179, 56, 1989
• Neurath, H.: The Activation of Zymogens, Adv Protein Chem 12, 319, 1957
• Neurath, H., and Dixon, G.: Structure and Activation of Trypsinogen and Chymotrypsinogen , Fed Proc 16, 791, 1957
• Neurath, H., and Schwert, G.: Crystalline Proteolytic Enzymes, Chem Rev 46, 69, 1950
• Nguyen, D., Mattras, H., Coletti-Previero, M., and Castro, B.: Design and Chemical Synthesis of a 32 Residue Chimeric Microprotein Inhibiting both Trypsin and Carboxypeptidase A , Biochem Biophys Res Commun 162, 1425, 1989
• Nishino, N., Mitsuyasu, N., and Izumiya, N.: Action of Trypsin on Synthetic Substrates. IV. Hydrolyses of Synthetic Insulin Fragments by Trypsin , J. Biochem. 75, 979, 1974
• Nord, F., and Bier, M.: On the Mechanism of Enzyme Action. LV. A Study of the Interaction between Calcium and Trypsin , Biochim Biophys Acta 12, 56, 1953
• Nord, F., Bier, M., and Terminiello, L.: On the Mechanism of Action. LXI. The Self Digestion of Trypsin, Calcium-Trypsin and Acetyltrypsin , Arch Biochem Biophys 65, 120, 1956
• Northrop, J., and Kunitz, M.: Crystalline Trypsin. I. Isolation and Tests of Purity, J Gen Physiol 16, 267, 1932
• Northrop, J., Kunitz, M., and Herriott, R.: Crystalline Enzymes,, Columbia Univ Press, 125, 1948
• Nureddin, A., and Ingami, T.: Chemical Modification of Amino Groups and Guanidino Groups of Trypsin. Preparation of Stable and Soluble Derivatives , Biochem J 147, 71, 1975
• Odorzynski,T., and Light, A.: Refolding of the Mixed Disulfide of Bovine Trypsinogen and Glutathione , J Biol Chem 254, 4291, 1979
• Ohlsson, K., and Tegner, H.: Anionic and Cationic Dog Trypsin. Isolation and Partial Characterization, Biochim Biophys Acta 312, 328, 1973
• Olafson, R., and Smillie, L.: Enzymic and Physicochemical Properties of Streptomyces griseus Trypsin , Biochemistry 14, 1161, 1975
• Olafson, R., Jurasek, L., Carpenter, M., and Smillie, L.: Amino Acid Sequence of Streptomyces griseus Trypsin. Cyanogen Bromide Fragments and Complete Sequence , Biochemistry 14, 1168, 1975
• Ooms, A., and van Dijk, C.: The Reaction of Organophosphorus Compounds with Hydrolytic Enzymes - III. The Inhibition of Chymotrypsin and Trypsin, Biochem Pharmacol 15, 1361, 1966
• Pace, C., and Barrett, A.: Kinetics of Tryptic Hydrolysis of the Arginine-Valine Bond of Folded and Unfolded Ribonuclease T1 , Biochem J 219, 411, 1984
• Perkal, M., Marks, C., Lorber, M., and Marks, W.: A Three-Year Experience with Serum Anodal Trypsinogen as a Biochemical Marker for Rejection in Pancreatic Allografts - False Postives, Tissue Biopsy, Comparison with Other Markers, and Diagnostic Strategies , Transplantation 53, 415, 1992
• Perlmutter, D., Joslin, G., Nelson, P., Schasteen, C., Adams, S., and Fallon, R.: Endocytosis and Degradation of alpha-1-Antitrypsin-Protease Complexes Is Mediated by the Serpin-Enzyme Complex (SEC) Receptor , J Biol Chem 265, 16713, 1990
• Pitotti, A., Maurich, V., Moneghini, M., Franchi, G., and Lencioni, E.: A Sensitive High-Performance Liquid Chromatographic Assay for Trypsin-Like Enzymes, J Pharm Biomed Anal 6, 121, 1988
• Polanowski, A., Cieslar, E., Otlewski, J., Nienartowicz, B.,Wilimowska-Pelc, A., and Wilusz, T.,: Protein Inhibitors of Trypsin from the Seeds of Cucurbitaceae Plants , Acta Biochim Pol 34, 395, 1987
• Poncz, L., and Dearborn, D.: The Resistance to Tryptic Hydrolysis of Peptide Bonds Adjacent to N-epsilon, N-Dimethyllysyl Residues , J Biol Chem 258, 1844, 1983
• Porter, W., and Preston, J.: Retention of Trypsin and Chymotrypsin Proteolytic Activity in Sodium Dodecyl Sulfate Solutions , Anal Biochem 66, 69, 1975
• Ram, J., Terminiello, L., Bier, M., and Nord, F.: On the Mechanism of Enzyme Action. LVIII. Acetyltrypsin, A Stable Trypsin Derivative , Arch Biochem Biophys 52, 464, 1954
• Rayasduarte, P., Bergeron, D., and Nielsen, S.: Screening of Heat-Stable Trypsin Inhibitors in Dry Beans and Their Partial Purification from Great Northern Beans (Phaseolus-Vulgaris) Using Anhydrotrypsin Sepharose Affinity Chromatography, J Agric Food Chem 40, 32, 1992
• Read, R., Brayer, G., Jurasek, L., and James, M.: Critical Evaluation of Comparative Model Building of Streptomyces griseus Trypsin , Biochemistry 23, 6570, 1984
• Reeck, G., and Neurath, H.: Pancreatic Trypsinogen from the African Lungfish , Biochemistry 11, 503, 1972
• Reichart, E., Boerkmann, P., Vignaud, J., and Plenat, F.: Experimental Emphysema Following One Intravenous Infusion of Trypsin , Exp Lung Res 18, 45, 1992
• Ridderknecht, H., Fleming, R., and Geokus, M.: Effect of alpha-2 Macroglobulin on Some Kinetic Parameters of Trypsin , Biochim Biophys Acta 377, 158, 1975
• Riechmann, L., and Kasche, V.: Kinetic Studies on the Mechanism and the Specificity of Peptide Semisynthesis Catalyzed by the Serine Proteases alpha-Chymotrypsin and beta-Trypsin , Biochem Biophys Res Commun 120, 686, 1984
• Robinson, N., Neurath, H., and Walsh, K.: Preparation and Characterization of Guanidated Trypsinogen and E-Guanidinated Trypsin , Biochemistry 12, 414, 1973
• Robinson, N., Neurath, H., and Walsh, K.: The Relation of the alpha-Amino Group of Trypsin to Enzyme Function and Zymogen Activation , Biochemistry 12, 420, 1973
• Royer, G., and Uy, R.: Evidence for the Induction of a Conformational Change of Bovine Trypsin by a Specific Substrate at pH 8.0 , J Biol Chem 248, 2627, 1973
• Ryltsev, V., and Virnik, R.: Kinetic Study on Isolation of Trypsin Immobilized on Dialdehyde Cellulose During Hydrolytic Destruction, Antibiot Chemother 34, 202, 1989
• Sanders, M., Walsh, K., and Arnon, R.: Immunological Cross-Reaction Between Trypsin and Chymotrypsin as a Guide to Structural Homology , Biochemistry 9, 2356, 1970
• Sarkany, R., and Moreland, B.: Enhancement of the Autocatalytic Activation of Trypsinogen to Trypsin by Bile and Bile Acids , Biochim Biophys Acta 839, 262, 1985
• Sawada, H., Kawahigashi, M., Yokosawa, H., and Ishii, S.: Trypsin-like Enzyme from Eggs of the Ascidian (Protochordate) Halocnthia roretzi , J Biol Chem 260, 15694, 1985
• Schaffer, N., Engle, R., Simet, L., Drisko, D., and Harshman, S.: Phosphopeptides from Chymotrypsin and Trypsin after Inactivation of P³² Labeled DFP and Sarin, Fed Proc 15, 347, 1956
• Schilling, R., and Mitra, A.: Degradation of Insulin by Trypsin and Alpha-Chymotrypsin , Pharm Res 8, 721, 1991
• Schroeder, D., and Shaw, E.: Chromatography of Trypsin and Its Derivatives. Characterization of a New Active Form of Bovine Trypsin , J Biol Chem 243, 2943, 1968
• Schwert, G., and Takenaka, Y.: A Spectrophotometric Determination of Trypsin and Chymotrypsin , Biochim Biophys Acta 16, 570, 1955
• Schwert, G., Neurath, H., Kaufman, S., and Snoke, J.: The Specific Esterase Activity of Trypsin, J Biol Chem 172, 221, 1948
• Shaw, E., and Glover, G.: Further Observations on Substrate-Derived Chloromethyl Ketones that Inactivate Trypsin , Arch Biochem Biophys 139, 298, 1970
• Shtelzer, S., Rappoport, S., Avnir, D., Ottolenghi, M., and Braun, S.: Properties of Trypsin and of Acid Phosphatase Immobilized in Sol-Gel Glass Matrices , Biotechnol Appl Biochem 15, 227, 1992
• Sipos, T., and Merkel, J.: An Effect of Calcium Ions on the Activity, Heat Stability, and Structure of Trypsin , Biochemistry 9, 2766, 1970
• Smillie, L., and Kay, C.: Abnormal Tyrosine Ionization and Configurational Changes of Trypsinogen in Alkaline Solutions, J Biol Chem 236, 112, 1961
• Smillie, L., and Neurath, H.: Reversible Inactivation of Trypsin by Anhydrous Formic Acid , J Biol Chem 234, 355, 1959
• Smith, R., and Shaw, E.: Pseudotrypsin. A Modified Bovine Trypsin Produced by Limited Autodigestion , J Biol Chem 244, 4704, 1969
• Spencer, P., Titus, J., and Spencer, R.: Direct Fluorimetric Assay for Proteolytic Activity Against Intact Proteins , Anal Biochem 64, 556, 1975
• Stevenson, K., and Voordouw, J.: Characterization of Trypsin and Elastase from the Moose (Alces alces). I. Amino Acid Composition and Specificity Towards Polypeptides , Biochim Biophys Acta 386, 324, 1975
• Stewart, J., Lee, H., and Dobson, J.: Evidence for a Functional Carboxyl Group in Trypsin and Chymotrypsin, J Am Chem Soc 85, 1537, 1963
• Stewart, K.: A Method for Automated Analyses of the Activities of Trypsin, Chymotrypsin and Their Inhibitors , Anal Biochem 51, 11, 1973
• Stroud, R., Kay, L., and Dickerson, R.: The Structure of Bovine Trypsin: Electron Density Maps of the Inhibited Enzyme at 5 Å and at 27 Å Resolution , J Mol Biol 83, 185, 1974
• Sturzebecher, J.: Stable Acyl-Derivatives of Trypsin-like Enzymes. Preparation, Kinetics, Application , Biomed Biochim Acta 45, 1405, 1986
• Tallan, H.: Chromatography of Trypsinogen , Biochim Biophys Acta 27, 407, 1958
• Tanaka, T., McRae, B., Cho, K., Cook, R., Fraki, J., Johnson, D., and Powers, J.: Mammalian Tissue Trypsin-like Enzymes. Comparative Reactivities of Human Skin Tryptase, Human Lung Tryptase, and Bovine Trypsin with Peptide 4-nitroanilide and Thioester Substrates , J Biol Chem 258, 13552, 1983
• Taran, L., and Smovdyr, I.: Comparative Kinetic Investigations of the Primary Specificity of Bovine and Salmon Trypsins. Russian , Biochem Z 57, 39, 1992
• Terminiello, L., Ram, S., Bier, M., and Nord, F.: On the Mechanism of Enzyme Action. LX. Acyl Derivatives of Trypsin , Arch Biochem Biophys 57, 252, 1955
• Tietze, F.: Molecular-Kinetic Properties of Crystalline Trypsinogen , J Biol Chem 204, 1, 1953
• Tisljar, U., and Denker, W.: A Sensitive Assay for Proteolytic Activity Using Fluorescein-Labeled Gelatin Coupled to Sepharose 4B as Substrate , Anal Biochem 152, 39, 1986
• Travis, J., and Roberts, R.: Human Trypsin. Isolation and Physical Chemical Characterization , Biochemistry 8, 2884, 1969
• Ueno, Y., and Morihara, K.: Use of Immobilized Trypsin for Semisynthesis of Human Insulin , Biotechnol Bioeng 33, 126, 1989
• Ueno, Y., and Morihara, K.: Use of Immobilized Trypsin for Semisynthesis of Human Insulin , Biotechnol Bioeng 33, 126, 1989
• van Gunsteren, W., and Karplus, M.: Protein Dynamics in Solution and in a Crystalline Environment: A Molecular Dynamics Study , Biochemistry 21, 2259, 1982
• Vandermeers, A., and Christophe, J.: Purification, Potential Enzymatic Activity and Amino Acid Composition of Chymotrypsinogen and Trypsinogens from Rat Pancreas. French , Biochim Biophys Acta 188, 101, 1969
• Vandermeers, A., Vanaermeers-Piret, M., Rathe, J., and Christophe, J.: Substrate Activation of Rat Trypsins 1 and 2 , Arch Biochem Biophys 159, 492, 1973
• Vincent, J., Lazdunski, M., and Delaage, M.: On the Use of Tetranitromethane as a Nitrate Reagent. The Reaction of Phenol Side-Chains in Bovine and Porcine Trypsinogens and Trypsins , Eur J Biochem 12, 250, 1970
• Walde, P., Peng, Q., Fadnavis, N., Battistel, E., and Luisi, P.: Structure and Activity of Trypsin in Reverse Micelles , Eur J Biochem 173, 401, 1988
• Walker, J., and Keil, B.: Purification and Characterization of Different Active Forms of Pork Trypsin , Eur J Biochem 32, 486, 1973
• Walsh, K.: Trypsinogens and Trypsins of Various Species, Methods in Enzymology Vol. 19,G. Perlmann and L. Lorand, Academic Press, NY, 41, 1970
• Walsh, K., and Neurath, H.: Trypsinogen and Chymotrypsinogen as Homologous Proteins , Proc Natl Acad Sci U S A 52, 884, 1964
• Walsh, K., Kauffman, D., Sampath Kumar, K., and Neurath, H.: On the Structure and Function of Bovine Trypsinogen and Trypsin , Proc Natl Acad Sci U S A 51, 301, 1964
• Wang, D., Wu, K., and Feinman, R.: Dissociability of Enzyme-alpha-2-Macro Globulin Complexes , Arch Biochem Biophys 222, 117, 1983
• Watanabe, T., and Ogasawara, N.: Purification and Properties of Multiple Forms of Mouse Trypsinogen , Biochim Biophys Acta 717, 439, 1982
• Weil, L., and Timasheff, S.: The Enzymic Activity of Trypsin Autolysis Products , Arch Biochem Biophys 116, 252, 1966
• Willstatter, R., Waldschmidt-Leitz, E., Dunaiturria, S., and Kunstner, G.: Hoppe-Seylers Z Physiol Chem 161, 191, 1926
• Wong, S., and Shaw, E.: Differences in Active Center Reactivity of Trypsin Homologs. Specific Inactivation of Thrombin by Nitrophenyl p-Amidinophenylmethanesulfonate , Arch Biochem Biophys 161, 536, 1974
• Woodward, C., Ellis, L., and Rosenberg, A.: Solvent Accessibility in Folded Proteins. Studies of Hydrogen Exchange in Trypsin , J Biol Chem 250, 432, 1975
• Wu, K., Wang, D., and Feinman, R.: Inhibition of Proteases by alpha-2-Macroglobulin. The Role of Lysyl Amino Groups of Trypsin in Covalent Complex Formation , J Biol Chem 256, 10409, 1981
• Yamashina, I.: The Action of Enterokinase on Trypsinogen , Biochim Biophys Acta 20, 433, 1956
• Zhao, Q., Kovach, I., Bencsura, A., and Papathanassiu, A.: Enantioselective and Reversible Inhibition of Trypsin and alpha-Chymotrypsin by Phosphonate Esters , Biochemistry 33, 8128, 1994
• Zhou, J., Liu, C., and Tsou, C.: Kinetics of Trypsin Inhibition by Its Specific Inhibitors , Biochemistry 28, 1070, 1989

Up: Worthington Enzyme Manual